NSG 124 - Pharmacology
Exam 1
Question:
Spasticity
Answer:
Baclofen, dantrolene, cyclobenzaprine, tizpizandine
Question:
Baclofen
Answer:
Reduces spasticity for multiple sclerosis and spinal cord injuries
short half life 4-4.5
CNS drowsiness, dizziness, fatigues, weakness GI constipation, urinary rentention
MUST TAPPER OFF 1 / 3
Question:
Dantrolene (Tantrum)
Answer:
Works directly on skeletal muscle, minimal effects on contractions of the smooth and cardiac muscle
Half-life 4-11hrs
adverse effects Hepatic toxicity, muscle weakness, drowsiness, diarrhea
Question:
Cyclobenzaprine (Flexeril)
Answer:
skeletal muscle relaxant, CNS depressant relief of muscle spasms and associate pain
Most common drug
CNS- drowsiness, dizziness, fatigue Dry-mouth, blurred vision, tachycardia, constipation Contradictions NAOIs (antidepressants) cyclobenzaprine, alcohol, and other CNS depressants
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Question:
Tizanidine (Zanaflex)
Answer:
Reduces muscle spasticity
unlabeled- acute back pain, tension headaches
Hepatic toxicity drowsiness, dizziness, lightheaded hypotension, bradycardia, hallucination,
Question:
Diazepam (Valium)
Answer:
Benzodiazepine, muscle relaxant, anxiety, acute alcohol withdrawal,
dizziness, drowsiness, hypotension, constipation, diarrhea, weight gain, dependency
Question:
local anesthetics
Answer:
produce loss of feeling and affect a local area only
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