NSG 552 - Psychopharmacology
Exam 1
Question:
What antipsychotic medication is likely to have the least amount of weight gain?
Answer:
Ziprasidone
Question:
What antipsychotic medication is least likely to result in metabolic syndrome?
Answer:
Haloperidol
Question:
What antipsychotic medications are least likely to cause increased prolactin?
Answer:
Aripiprazole, Asenapine, Clozapine, Quetiapine, Olanzapine 1 / 4
Question:
What antipsychotic medications are least likely to cause QT elongation?
Answer:
Haloperidol, Olanzapine, Aripiprazole
Question:
What antipsychotic medications are least likely to cause EPS?
Answer:
Clozapine, Quetiapine
Question:
What are the four steps to monitor for metabolic syndrome?
Answer:
1) Obtain Baseline -> weight, BMI, fasting glucose and lipids, BP, EKG 2) Recheck weight+BMI at 4 weeks, 8 weeks, 12 weeks, 6 months, quarterly, and annually 3) Check fasting glucose and lipids at Biannually 4) If metabolic syndrome is suspected then switch agents, lower dose, and/or add metformin
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Question:
T/F ETOH use increases risk for TD?
Answer:
TRUE
Question:
Akasthesia
Answer:
A state of agitation, distress, and restlessness that is an occasional side-effect of antipsychotic and antidepressant drugs
Question:
Dystonia
Answer:
Involuntary muscle contraction that cause repetitive or twisting movements.
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Question:
Pseudo-parkinsonism
Answer:
AKA DRUG INDUCED PARKINSONISM is a reversible condition that resembles parkinsonism. Parkinsonism refers to any condition that causes the movement irregularities seen in Parkinson's disease, a brain disorder.
Question:
How to manage EPS?
Answer:
1) Add benztropine, Benadryl, amantadine DO NOT USE FOR
PROPHLAYXIS DUE TO SIDE EFFECTS
2) Or Consider switching medications. (EPS is less likely to be caused by clozapine or quetiapine)
Question:
Name 3 options to treat psychotic agitation?
Answer:
1) PO risperidone + lorazepam 2) IM haloperidol + lorazepam 3) Asenapine can be given sublingual to TOP OFF or provide additive effect to current APS treatment
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