NSG 6005 Week 2 Pharmacology Quiz

NSG 6005 Week 2 Pharmacology Quiz The major reason for not crushing a sustained release capsule is that, if crushed,

the coated beads of the drugs could possibly result in:

• Disintegration
• Toxicity
• Malabsorption
• Deterioration

(ANS- o Toxicity

Drugs that have a significant first pass effect:

• Must be given by enteral (oral) route only
• Bypass the hepatic circulation
• Are rapidly metabolized by the liver and may have little if any desired action
• Are converted by the liver to more active in fat-soluble forms

(ANS-

• Are rapidly metabolized by the liver and may have little if any desired action

When obtaining a drug history from Harold, he gives you a complete list of his prescription medications. He denies taking any other drugs, but you find that he

occasionally takes aspirin for his arthritis flare-ups. This is an example of:

• His appropriately only telling you about his regularly prescribed medications
• His hiding information regarding his inappropriate use of aspirin from you 1 / 2

• His common misconception that intermittently taking OTC medications are not

an important part of his drug history

• A common misuse of OTC aspirin

(ANS

• o His common misconception that intermittently taking OTC medications are not

an important part of his drug history

Drugs that use CYP3A4 isoenzymes for metabolism may:

• Induce the metabolism of another drug
• Inhibit the metabolism of another drug
• Both A and B
• Neither A nor B

(ANS- o Both A and B

A twenty four year old male received multiple fractures in a motor vehicle accident that required significant amounts of opioid medication to treat his pain. He is at risk for Type ____ ADR when he no longer requires the opioids.

• A
• C
• E
• G

(ANS- o E

• / 2