NU 641 Quiz 3 Exam Questions with CORRECT ANSWER s
Question : rugs used for parkinson's
CORRECT ANSWER : dopaminergic
anticholinergic
Question : levodopa - how is it used and why combined with
carbidopa CORRECT ANSWER : how used: as dopamine replacement in parkinsons undergoes conversion to DA in brain and activates DA receptors.
why: blocks destruction of levodopa in periphery to decrease
amount of decarboxylation so more drug can enter CNS and increase dopamine synthesis (ties up vitamin b 6)
Question : patient education levodopa
CORRECT ANSWER : avoid high protein meals delays
drug
can have on/off period - tell MD
N/V common take with fruits/veggies
monitor cardiac s/s and renal/liver function
psychosis see MD
Question : what can't you combined levodopa with?
CORRECT ANSWER : antipsychotics decrease
effectiveness
MAO increase toxicity
Question : pramipexole - what is it used for?
CORRECT ANSWER : - parkinsons as dopamine agonist in
early stages of PD to improve motor function and combined with levodopa in advance stages to reduce fluctuations of motor control
restless leg syndrome
Question : SE pramipexole
CORRECT ANSWER: nausea, dizziness, somulence,
insomnia, constipation, hallucinations, SLEEP ATTACKS & IMPULSE CONTROL DISORDERS (screen for this)
has less sleep attacks than other agents
Question : what drug increases pramipexole levels?
CORRECT ANSWER : cimetidine
Question : what drug is used to treat n/v in apomorphine
CORRECT ANSWER : trimethobenzamide (Tigan) 3 days
before taking. Cannot combine with other antimetics risk for postural hypotension and decrease effectiveness of drug.
Question : what is apomorphine used for?
CORRECT ANSWER : acute hypomobility during off
episodes in advance PD given by injection
Question : apomorphine SE
CORRECT ANSWER : Severe N/V
Hypotension hyper sexuality
Question : cholinesterase agents for ALZ
CORRECT ANSWER: donzepil
galantamine rivastigmine
Question : which alz med is irreversible inhibition?
CORRECT ANSWER : rivastigmine
Question : how do cholinesterase agents work
CORRECT ANSWER : prevent breakdown of ACH and
increase availability of ach at synapses. important for ALZ to