NU664C Midterm Exam Q & A Already Passed!!Know the route of administration for newer agent asenapine (Saphris) and what instructions should be given to the patient regarding administration. Answer- Sublingual Know and describe the top atypical antipsychotic with greatest incidence of prolonged QTc interval. Answer- Ziprasidone (Geodon).Know which antipsychotics have specific instructions for minimum food intake or diet restrictions. Answer- Lurasidone (Latuda) Know an alternative atypical antipsychotic for a patient who has developed diabetes and has a significant weight gain from treatment with olanzapine. Answer- Aripiprazole (Abilify) Know whether a patient is demonstrating efficacy to clozapine 500 mg/day if this week's granulocyte count is less than 500mm3. What is the most appropriate recommendation for drug therapy? Answer- Discontinue and do not re-start Know the common effects of smoking along with antipsychotic drug therapy such as olanzapine. Answer- Decreases the plasma levels of Olanzapine (Zyprexa) because of its metabolism at CYP450 enzyme.Know what a painful muscle spasm with neck muscles pulling a patient's head to the side called and Name a common drug therapy to relieve this symptom. Answer- Dystonia Know the role of buspirone in the treatment of anxiety and the recommended dose and time for onset of action. Answer- Takes 3 to 4 weeks for full effect Know what medication may be an option for patients noncompliant on antipsychotics resulting in multiple hospital stays. Answer- Risperdal Consta (risperidone) Know baseline labs and vital measurements tests for the patient who will be prescribed an antipsychotic such as quetiapine (Seroquel). Answer- Lipid, Fasting Blood Sugar, Family History **NOT CPK** Describe common side effects/disadvantages of antihistamines. Answer- anticholinergic effects Identify 3-4 disorders/situations when benzodiazepines may be indicated. Answer- Alcohol withdrawal, Benzodiazepine withdrawal, Acute Agitation, Panic Attack, Sleep Disorder, Seizures
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