NU664C Midterm Exam Q&A Well Answered Know the route of administration for newer agent asenapine (Saphris) and what instructions should be given to the patient regarding administration. - Correct Answer Sublingual Know and describe the top atypical antipsychotic with greatest incidence of prolonged QTc interval. - Correct Answer Ziprasidone (Geodon).Know which antipsychotics have specific instructions for minimum food intake or diet restrictions. - Correct Answer Lurasidone (Latuda) Know an alternative atypical antipsychotic for a patient who has developed diabetes and has a significant weight gain from treatment with olanzapine. - Correct Answer Aripiprazole (Abilify) Know whether a patient is demonstrating efficacy to clozapine 500 mg/day if this week's granulocyte count is less than 500mm3. What is the most appropriate recommendation for drug therapy? - Correct Answer Discontinue and do not re-start Know the common effects of smoking along with antipsychotic drug therapy such as olanzapine. - Correct Answer Decreases the plasma levels of Olanzapine (Zyprexa) because of its metabolism at CYP450 enzyme.Know what a painful muscle spasm with neck muscles pulling a patient's head to the side called and Name a common drug therapy to relieve this symptom. - Correct Answer Dystonia Know the role of buspirone in the treatment of anxiety and the recommended dose and time for onset of action. - Correct Answer Takes 3 to 4 weeks for full effect Know what medication may be an option for patients noncompliant on antipsychotics resulting in multiple hospital stays. - Correct Answer Risperdal Consta (risperidone) Know baseline labs and vital measurements tests for the patient who will be prescribed an antipsychotic such as quetiapine (Seroquel). - Correct Answer Lipid, Fasting Blood Sugar, Family History **NOT CPK**
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