NUR 105 Test 1
- Heparin
Answer Anticoagulants
- Heparin actions
Answer inhibits thrombus & clot production by blocking the conversion of prothrombin to thrombin & fibrinogen to fibrin
- Heparin indications
Answer prevention & treatment of venous thrombosis & pulmonary emboli
treatment of atrial fibrillation with embolization diagnosis & treatment of disseminated intravascular coagulation prevention of clotting in blood samples & heparin-lock sets
- Heparin adverse effects
Answer loss of hair bruising & bleeding (gums to hemorrhage) chills, fever,
osteoporosis suppression of renal function
- Heparin contraindications
Answer hemorrhagic disorders recent trauma or surgery
spinal puncture, GI ulcers IUD placement, threatened abortion indwelling catheters
TB 1 / 3
- Heparin nursing considerations
Answer whole blood clotting time (WBCT) 2.5-3 times control OR APTT 1.5-3 times control
evaluate for any sign of blood loss (bruising) safely measures (no contact sports, electric razor) antidotes on standby avoid smoking
- Heparin drug to drug interactions
Answer increased bleeding when combined with oral anticoagulants, salicylates, penicillins, or cephalosporins
decreased anticoagulation with combined with nitroglycerin
- Heparin overdose antidote
Answer protamine sulfate
- Heparin cautions
Answer heart failure, thyrotoxicosis, senility, psychosis, diarrhea, fever
- Urokinase
Answer Thrombolytic agents
- Urokinase actions
Answer converts endogenous plasminogen to plasmin, which breaks down fibrin clots, fibrinogen, & other plasma proteins
lyses thrombi & emboli 2 / 3
- Urokinase indications
Answer lysis of pulmonary emboli or pulmonary emboli with unstable hemodynamics
- Urokinase adverse effects
Answer Bleeding, Headache, pain, fever angioneurotic edema, hypotension cardiac arrhythmias skin rash, breathing difficulties bronchospasm, anaphylactic shock
- Urokinase contraindications
Answer Recent surgery or major trauma (CPR) active internal bleeding
CVA within the last 2 months aneurysm organ biopsy recent serious GI bleed blood clotting defects uncontrolled HTN liver disease
- Urokinase drug to drug interactions
Answer anticoagulant antiplatelet
- Urokinase nursing considerations
- Phenytoin
- / 3
Answer discontinue heparin before use monitor coagulation studies increased precautions against bleeding during invasive procedures
Answer hydantoins