NUR 162 Test 1
- Excitatory or inhibitory? Norepinephrine
Answer Excitatory
- Excitatory or inhibitory? Epinephrine
Answer Excitatory
- Excitatory or inhibitory? Dopamine
Answer Excitatory
- Excitatory or inhibitory? Acetylcholine
Answer Excitatory or inhibitory
- Excitatory or inhibitory? Serotonin
Answer Inhibitory
- Excitatory or inhibitory? Gamma-aminobutyric acid (GABA)
Answer Inhibitory
- What type of neurotransmitter is histamine?
Answer Neuromodulator
- What does histamine control? 1 / 4
Answer Controls alertness, gastric secretions, cardiac stimulation, peripheral allergic response
- What does GABA do?
Answer Modulates other neurotransmitters
- What does serotonin control?
Answer Controls food intake, sleep and wakefulness, temperature regulation, pain control, sexual behaviors, regulation of emotions
- What does acetylcholine control?
Answer Controls sleep and wakefulness cycle; signals muscles to become alert
- What does dopamine control?
Answer Controls complex movements, motivation, cognition; regulates emotional response
- What does epinephrine control?
Answer Controls "fight or flight" response
- What does norepinephrine control?
Answer Changes in attention, learning and mem- ory, sleep and wakefulness, mood
- Excess norepinephrine can cause
Answer Severe anxiety disorders 2 / 4
- A deficit in norepinephrine can cause
Answer Memory loss, social withdrawal and depression
- Excess dopamine can cause
Answer Schizophrenia
- A deficit in dopamine can cause
Answer Parkinsons disease
- Mechanism of action for ALL antipsychotic drugs
Answer Block receptors for the neurotransmitter dopamine
- Conventional (first generation) antipsychotics are potent antagonists (blockers) of D2, D3
and D4. Blocking D2 causes
Answer Extrapyramidal side effects
- Atypical (2nd generation) antipsychotics MOA
Answer Inhibit the reuptake of sero- tonin (which increases their effect of treating the depressive aspects of schizophre- nia)
- Atypical (2nd generation) antipsychotics are weak blockers of D2 which means
Answer A lower incidence of extrapyramidal side effects
- Paliperidone is chemically similar to
Answer 3 / 4
Risperidone (except Paliperidone is extended release)
- Weight gain is more likely with what generation antipsychotics?
Answer 2nd gen- eration (atypical), except Ziprasidone
- What two antipsychotics is weight gain most significant in?
Answer Clozapine and Olanzapine
- What is the warning that all atypical (2nd generation) antipsychotics must have on the box?
Answer Increased risk for hyperglycemia and diabetes
- What route is Asenapine given?
Answer Sublingual
- What is important patient teaching regarding the application of Asenap- ine?
Answer Avoid food or drink for 10-15 minutes after the medication dissolves
- MOA of dopamine system stabilizers (3rd generation) antipsychotics?
Answer 3rd generation antipsychotics preserve or enhance dopaminergic transmission when it is too low and reduces it when it is too high
- What is DSM-5-TR
- / 4
Answer Diagnostic and Statistical Manual of Mental Disorders