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NUR 213 Test 3
- Contraindications for Antirejection Immunosuppressants
Answer Active infections, lymphoma Pregnancy, breastfeeding Concomitant vaccine administration Renal or hepatic impairment
- Tacrolimus and Sirolimus boxed warning
Answer infants and children, clients under- going liver transplant
- Cyclosporine boxed warning
Answer systemic hypertension and nephrotoxicity
- Live attenuated vaccines
Answer
- Contain pathogen that have been weakened in the laboratory
- No longer able to cause infection
- Still able to trigger protective immune response
- Inactivated vaccines
Answer
- Use a pathogen that has been killed in the laboratory
- No longer able to replicate or cause infection
- Still able to trigger a protective immune response
- Subunit, recombinant, and polysaccharide vaccines
Answer Contain just the portion of pathogen that stimulates the immune response
- Conjugated Vaccines
Answer Stronger and longer lasting immune response
- Toxoid vaccines
Answer Inactivated toxins produced by pathogens protect against tetanus and diphtheria
- mRNA Vaccines
Answer 1 / 3
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- Codes for a harmless viral protein
- Unable to cause disease
- Capable of triggering an immune response
- First generation antihistamines (examples)
Answer
- chlorpheniramine
- diphenhydramine
- hydroxyzine
- promethazine
- Second generation antihistamines (examples)
Answer
- loratadine
- desloratadine
- fexofenadine
- levocetirizine
- First generation antihistamine
-cetirizine
Answer
- can more easily cross the blood brain barrier
- Lethargic, can sedate
- second generation antihistamines
Answer better for use during the day
- indications for first generation antihistamines
Answer Allergic rhinitis Allergic conjunctivitis Urticaria Anaphylaxis
Common cold Nausea and vomiting Motion sickness Insomnia
- Indications for second generation antihistamines
Answer Allergic rhinitis Allergic conjunctivitis Urticaria Anaphylaxis Common cold
- example of methylxanthines
Answer 2 / 3
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theophylline
- mechanism of action of theophylline
Answer Enters smooth muscles of the airways and inhibits the enzyme phosphodiesterase, leading to smooth muscle relaxation
- Theophylline
Answer Can be used in asthma and COPD Bronchial smooth muscle relaxation Dilation of the narrowed airways and improved air flow
- Bronchodilators
Answer theophylline is a
- Mechanism of Biologic Agents -
TNF Blockers (etanercept (Enbrel), infliximab (Remicade, Renflexis, Avsola, Inflectra), adalimumab (Humira))
Answer Prevent TNF from attaching to its re- ceptor ’ suppress immune response
- Mechanism of Biologic Agents - IL-1 inhibitor, IL-6 inhibitor, IL-17A in- hibitor (anakinra
(Kineret) tocilizumab (Actemra, Actemra ACTPen) secukinumab (Cosentyx, Cosentyx Sensoready Pen))
Answer Prevent IL-1, IL-6, or IL-17A from attaching to their receptors ’ suppress immune response
- Nursing considerations for inhalers
Answer Shake mdi canister Exhale all air out of the lungs Put spacer mouthpiece to mouth, make tight seal Press down in mda Inhale slowly and deeply, hold breath for 5-10 seconds then fully exhale If needs more than 1 puff, wait 1 min before 2nd puff Gargle and rinse the mouth to decrease thrust
- Spacer
Answer Promotes maximal delivery of medication to lungs
- Nursing Considerations for nasal decongestants
Answer Assess nasal passages before administration
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