NUR 220 Oncology 2
- Contact inhibition
Answer slow cell growth when contacted with other cell membranes
- G0 phase
Answer resting phase
- G1 phase
Answer end of mitosis to beginning of DNA synthesis
- S phase
Answer DNA synthesis and replication
- G2
Answer end of DNA synthesis and beginning of mitosis
- M phase
Answer mitosis and cell division phase (splitting)
- Lack of contact inhibition
Answer cancer occurs because of this
where proliferation is same rate of normal cell but they divide more frequently and haphazardly 1 / 2
- Oncogenes
Answer mutated genes that cause cancer Occurs when the cell divides too fast
- tumor suppressor genes
Answer slow down cell division in a normal cell this mechanism is inactivated with cancer and cells grow out of control this can be inherited
10. P53
Answer relates to bladder, breast, colorectal, esophagus, liver, lung and ovaries
- BRCA1 and BRCA2
Answer linked to breast and ovarian cancers
12. APC
Answer linked to colorectal cancer
- initiation (development of cancer)
Answer start of genetic mutation in the cell, some- thing has to cause this (radiation, chemicals, virus), it is IRREVERSIBLE
- Promotion (development of cancer)
Answer promoting agent, it is REVERSIBLE
- complete carcinogen
- / 2
Answer