NUR 280 Exam 2
- Wound healing is regulated by
Answer
- Chemokines
- Cytokines
- Growth factor
- Proteases
- What are the four phases of wound healing?
Answer
- Hemostasis
- Inflammation
- Proliferation
- Remodeling
- During Phase 1 (hemostasis)
Answer
Clotting and growth factors are released
- During Phase 2 (inflammation)
Answer
Vasodilatation, increased perfusion and capillary permeability (causes redness), chemotaxis and cellular activity (neutrophils attack bacteria, platelets to wound site, macrophages eat debris) 1 / 4
- During Phase 3 (proliferation)
Answer
Vascular tissue restored and granulation tissue fills deficit; fibroblasts make new collagen; high O2 demand
- During Phase 4 (remodeling)
Answer
Collagen fibers strengthen; can last 2 years; only ever reach 80% of original strength
- Trauma
Answer Injury/wound
- Venous hypertension
Answer
Leaky valves allow buildup of pressure in veins
- Lymphedema
Answer
Swelling of extremity due to obstructed lymph channel, nonpitting
- Vasculitis
Answer 2 / 4
An inflammation of the blood vessels that causes changes in the blood vessel walls
- Malignant
Answer Spreads
- Surgical dehiscence
Answer
Wound ruptures open along incision
- Arterial insufficiency
Answer
Slow or stop of blood flow through the arteries
- Pressure ulcers occur on
Answer
Bony areas due to pressure, friction, or shear
- Arterial ulcer
Answer
A wound that won't heal due to decreased blood flow
- Claudication 3 / 4
Answer
Limping
- Wet gangrene
Answer
Tissue necrosis associated with infection requires emergent debridement and drainage, followed by revascularization
- Dry gangrene
Answer
Necrosis not invasive; doesn't produce sepsis unless infected; revascularization performed first before amputating
- Dual venous system
Answer
Superficial saphrenous system and deep venous system
- Venous ulcers caused by
Answer
Failure of calf muscle to pump or valve incompe- tence
- Venous Leg Ulcer
Answer
Veins dilate and leak blood and serum into interstitial tissue; ulcers always associated with edema
- / 4