NUR 326 Antibiotics
- classes of antibiotics
Answer aminoglycosides carbapenems cephalosporins penicillins and penicillinase-resistant drugs fluoroquinolones sulfonamides tetracyclines antimycobacterials
- prototype drug for aminoglycosides
Answer Gentamicin
- MOA for gentamicin
Answer bactericidal - inhibits protein synthesis (gram -)
- indications for gentamicin
Answer reserved for serious infections
- how is gentamicin administered
Answer IM or IV
- contraindications for gentamicin
Answer renal disease, hepatic disease, hearing loss, pregnancy and lactation
- adverse effects of gentamicin
Answer neuro/ototoxicity, nephrotoxicity, and GI discom- fort
- what should you monitor with gentamicin 1 / 2
Answer cognition/hearing, kidney function, and hydration
- prototype drug for carbapenems
Answer ertapenem
- MOA for ertapenem
- indications for ertapenem
Answer bactericidal - inhibits cell membrane
Answer treatment of serious infection - pneumonia
- administration of ertapenem
Answer IM or IV
- contraindications for ertapenem
Answer seizure disorders, pregnancy/lactation
- adverse effects of ertapenem
Answer
- diff, N/V, dizziness
- what should you monitor when using ertapenem
Answer GI toxicity, CNS effects
- prototype drug for cephalosporins
Answer cefaclor
- MOA for cefaclor
Answer bactericidal and bacteriostatic - cell wall
- indications for cefaclor
- / 2
Answer gram + and gram - bacteria (respiratory, skin, middle ear infections)