NUR 600 EXAM 1 NEWEST 2025 ACTUAL EXAM

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NUR 600 EXAM 1 NEWEST 2025 ACTUAL EXAM

COMPLETE 150 QUESTIONS AND CORRECT

DETAILED ANSWERS (VERIFIED ANSWERS)

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Drugs are metabolized mainly by the liver via Phase I or Phase II reactions. The purpose of both of these types of reactions is

to:

• Inactivate prodrugs before they can be activated by target

tissues

• Change the drugs so they can cross plasma membranes
• Change drug molecules to a form that an excretory organ can

excrete

• Make these drugs more ionized and polar to facilitate

excretion - ANSWER-C. Change drug molecules to a form that an excretory organ can excrete

Once they have been metabolized by the liver, the metabolites

may be:

• More active than the parent drug
• Less active than the parent drug 1 / 4

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• Totally "deactivated" so that they are excreted without any

effect

• All of the above - ANSWER-D. All of the above

All drugs continue to act in the body until they are changed or excreted. The ability of the body to excrete drugs via the renal

system would be increased by:

• Reduced circulation and perfusion of the kidney
• Chronic renal disease
• Competition for a transport site by another drug
• Unbinding a nonvolatile drug from plasma proteins -

ANSWER-D. Unbinding a nonvolatile drug from plasma proteins

Steady state is:

• The point on the drug concentration curve when absorption

exceeds excretion

• When the amount of drug in the body remains constant
• When the amount of drug in the body stays below the MTC
• All of the above - ANSWER-B. When the amount of drug in

the body remains constant

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Two different pain meds are given together for pain relief. The

drug-drug interaction is:

• Synergistic
• Antagonistic
• Potentiative
• Additive - ANSWER-D. Additive

.Actions taken to reduce drug-drug interaction problems include

all of the following EXCEPT:

• Reducing the dose of one of the drugs
• Scheduling their administration at different times
• Prescribing a third drug to counteract the adverse reaction of

the combination

• Reducing the dosage of both drugs - ANSWER-C.

Prescribing a third drug to counteract the adverse reaction of the combination

Phase I oxidative-reductive processes of drug metabolism require certain nutritional elements. Which of the following would reduce or inhibit this process?

• Protein malnutrition
• Iron deficiency anemia 3 / 4

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• Both A and B
• Neither A nor B - ANSWER-D. Neither A nor B

The time required for the amount of drug in the body to decrease

by 50% is called:

• Steady state
• Half-life
• Phase II metabolism
• Reduced bioavailability time - ANSWER-B. Half-life

An agonist activates a receptor and stimulates a response. When

given frequently over time the body may:

• Up-regulate the total number of receptors
• Block the receptor with a partial agonist
• Alter the drug's metabolism
• Down-regulate the numbers of that specific receptor -

ANSWER-D. Down-regulate the numbers of that specific receptor

Drug antagonism is best defined as an effect of a drug that:

• Leads to major physiologic psychological dependence
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