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NUR565 MIDTERM EXAM AND STUDY GUIDE EXAM|
ADVANCED PHARMACOLOGY FUNDAMENTAL LATEST
2025/2026 ACTUAL EXAM |COMPLETE 300 QUESTIONS
AND CORRECT DETAILED ANSWERS (VERIFIED ANSWERS)
|ALREADY GRADED A+ |CHAMBERLAIN.
What is used to calculate a patients overdose risk? - ANSWER - MME total morphine milligram equivalent per day
When should you refer a patient to a pain specialist? - ANSWER - Referral to a pain specialist is required for patients who take 120 mg per day of morphine milligram equivalents
What is the PDMP? - ANSWER - Prescription Drug Monitoring Program Used to effectively track patient’s-controlled substance uses across different health facilities (in the same state)
When should Narcan be prescribed? - ANSWER - factors that increase risk for opioid overdose, such as history of overdose, history of substance use disorder, higher opioid dosages (≥50 MME/day), or concurrent benzodiazepine use, are present.
Behaviors that predict substance abuse - ANSWER - NIDA-Modified
ASSIST
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pg. 2 Examples of schedule II meds - ANSWER - Some examples of Schedule II
drugs are: combination products with less than 15 milligrams of
hydrocodone per dosage unit (Vicodin), cocaine, methamphetamine, methadone, hydromorphone (Deluded), meperidine (Demerol), oxycodone (OxyContin), fentanyl, Dexedrine, Adderall, and Ritalin
DEA description of scheduled drugs - ANSWER - Drugs, substances, and certain chemicals used to make drugs are classified into five (5) distinct categories or schedules depending upon the drug's acceptable medical use and the drug's abuse or dependency potential. The abuse rate is a determinate factor in the scheduling of the drug; for example, Schedule I drugs have a high potential for abuse and the potential to create severe psychological and/or physical dependence.
Treatment of chronic pain - ANSWER - Nonpharmacologic therapy and nonopioid pharmacologic therapy are preferred for chronic pain.Benefits > Risks Establish goals Start with immediate release meds start with the lowest effective dose eval within 1-4 wks.
What is methadone? - ANSWER - Nonpharmacologic therapy and nonopioid pharmacologic therapy are preferred for chronic pain.
What is the black box warning for methadone? - ANSWER - Methadone can cause life-threatening QT prolongation and severe respiratory depression. Because of the long half-life of methadone, it should be prescribed only by health care providers with special training in chronic pain management. 2 / 4
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factors for substance abuse - ANSWER - Drug related: availability, effect
and tolerability.
Predisposition: genetics, personality and psych
Environment: family, society, peer group, life events, stress
Benefit of using buprenorphine and naloxone - ANSWER - Buprenorphine/naloxone combinations like Suboxone work in the body by binding to opioid receptors, which help regulate hormones, physical movement, emotions, and pleasure.
Order of HTN medications typically prescribed - ANSWER - thiazide-type diuretic calcium channel blocker (CCB) angiotensin-converting enzyme inhibitor (ACEI) angiotensin receptor blocker (ARB).
What is the best antihypertensive for someone with diabetes? - ANSWER - ACEIs, ARBs, CCBs, and diuretics (in low doses).
best HTN med for pregnancy? - ANSWER - labetalol and methyldopa
What hen meds are contraindicated in pregnancy? - ANSWER - ACEIs, ARBs, and DRIs,
Clonidine - ANSWER - site of action: brainstem
Suppression of sympathetic outflow decreases sympathetic stimulation of the heart and blood vessels.
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Mecamylamine - ANSWER - site of action: Sympathetic ganglia
Ganglionic blockade reduces sympathetic stimulation of the heart and blood vessels.
Reserpine - ANSWER - site of action: Adrenergic nerve terminals
Reduced norepinephrine release decreases sympathetic stimulation of the heart and blood vessels.
What meds do not work as well for African Americans? - ANSWER - n contrast, monotherapy with β blockers or ACEIs is less effective in African Americans than in Caucasians. Nonetheless, β blockers and ACEIs should be used if they are strongly indicated for a comorbid condition
what to prescribe in response to fibrotic changes? - ANSWER - Sacubitril/valsartan (Entresto).Aldosterone Antagonists (Spiro lactone) Direct Renin Inhibitors β Blockers
effects of cardiac glycosides - ANSWER - Digoxin exerts a positive inotropic action on the heart. That is, the drug increases the force of ventricular contraction and can thereby increase cardiac output
what happens when digoxin and quinidine are combined? - ANSWER - when quinidine is Coad ministered with digoxin, quinidine inhibition of P-gp results in an increase in digoxin absorption and a reduction of digoxin elimination,
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