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NURS 5315 MSK EXAM 1 NEWEST 2025 ACTUAL
EXAM| ADVANCED PATHOPHYSIOLOGY EXAM |
COMPLETE QUESTIONS AND CORRECT
DETAILED ANSWERS (VERIFIED ANSWERS)
ALREADY GRADED A+| NEW!!
Which antigen is most strongly associated with ankylosing spondylitis?
- HLA-DR4
- HLA-B27
- HLA-A2
- HLA-B7 - Correct Answer - b. HLA-B27
What is a characteristic feature of ankylosing spondylitis on X-ray imaging?
- Osteophyte formation
- Erosive changes in metacarpophalangeal joints
- Bamboo spine
- Subcutaneous nodules - Correct Answer - c. Bamboo spine
The pathophysiology of ankylosing spondylitis primarily involves which structure?
- Synovial membrane
- Fibrocartilage at entheses
- Articular cartilage 1 / 3
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- Subchondral bone - Correct Answer - b. Fibrocartilage at entheses
Which postural change is associated with advanced ankylosing spondylitis?
- Increased lumbar lordosis
- Increased thoracic kyphosis
- Ulnar deviation of fingers
- Swan-neck deformity - Correct Answer - b. Increased thoracic
kyphosis
Which early symptom is most characteristic of ankylosing spondylitis?
- Morning stiffness improving with activity
- Symmetric joint swelling
- Pain relieved by rest
- Acute onset joint pain - Correct Answer - a. Morning stiffness
improving with activity
What is the primary pathophysiological hallmark of osteoarthritis?
- Synovial inflammation
- Loss of articular cartilage
- Autoantibody production
- Enthesitis - Correct Answer - b. Loss of articular cartilage
Which factor increases the risk of osteoarthritis? 2 / 3
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- Low body mass index
- HLA-B27 positivity
- Repetitive joint stress
- Acute infection - Correct Answer - c. Repetitive joint stress
Osteophyte formation in osteoarthritis is best described as:
- Proliferation of synovial cells
- Degeneration of cartilage
- Compensatory bone growth at joint margins
- Chronic inflammation of entheses - Correct Answer - c.
Compensatory bone growth at joint margins
Which symptom is most typical of osteoarthritis?
- Symmetric joint involvement
- Pain worsens with activity and improves with rest
- Prolonged morning stiffness (>1 hour)
- Constitutional symptoms like fever and weight loss - Correct Answer
- Pain worsens with activity and improves with rest
What is a common radiographic finding in osteoarthritis?
- Joint space narrowing
- Periarticular erosions
- Pannus formation
- Bamboo spine - Correct Answer - a. Joint space narrowing
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