pg. 1 NURS 5334 Newest 2024 -2025 Final Review/ Advanced Pharmacotherapeutics Final Exam Questions with Correct Detailed Answers (Verified Answers) Graded A+
Which of the following medications will not cause rebound headaches from overuse?
- Propranolol
- Sumatriptan
- Acetaminophen
- Ibuprofen - Correct Answer - A. Propranolol
Which of the following is best option for menstrual migraine?
- Sumatriptan at onset
- Propranolol as preventive
- Low dose estrogen about 3 days prior to menses
- Sertraline about 3 days prior to menses. - Correct Answer - C. Low dose estrogen
about 3 days prior to menses
Which of the following foods can trigger migraines?
- Shell fish
- Hot dog
- Watermelon
- Peanuts - Correct Answer - B. Hot dog
What are three drugs that can be combined with Hydrocodone? (Pain Management Mod 3) - Correct Answer - Aspirin 1 / 4
pg. 2 Acetaminophen Ibuprofen
Benzodiazepines and CNS depressants can be paired with acetaminophen- hydrocodone, True or False? - Correct Answer - False, this could lead to respiratory depression
Why would you give a patient Buprenorphine for maintenance once they recovered from opioid abuse? - Correct Answer - Partial opioid agonist that activated opioid receptors but produces less degree of euphoria and physical dependence compared to a full agonist
Why would you give a patient Naltrexone for maintenance once they recovered from opioid abuse? - Correct Answer - Naltrexone is an opioid antagonist that blocks the euphoric and sedative effects of opioids.
What are 3 side effects of Hydrocodone? - Correct Answer - Constipation Respiratory depression Addition
What's the MOA of Sumatriptan? (-triptan) - Correct Answer - Selective agonist for serotonin 5HT receptors on intracranial blood vessels and sensory nerves of the trigeminal system, causes VASOCONSTRICTION and reduces neurogenic inflammation
What is the supplement Feverfew used for? - Correct Answer - Migraine Prophylaxis
Which types of drugs cannot be combined with Feverfew? - Correct Answer - Antiplatelet Anticoagulants
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pg. 3 Increased risk of bleeding in patients taking antiplatelets (Aspirin) and anticoagulants (Warfarin)
How much Folic acid need to be given for a Folic Acid Deficiency? - Correct Answer - Give 1-2mg/day PO for a deficiency
Which of the following medications is a Serotonin 1B1D receptor agonist?
- Sumatriptan
- Ergotamine
- Topiramate
- Amitriptyline - Correct Answer - A. Sumatriptan
Butterbur can help as preventive for migraine therapy. Which of the following side effects may occur? •
- Renal failure
- Liver damage
- Anemia
- Thrombocytopenia - Correct Answer - B. Liver damage
What are the 3 main classes of opioid receptors? - Correct Answer - Mu Kappa Delta
Which of the following will reverse the effects caused by opioid agonists?
- Naloxone
- Meperidine
- Epinephrine
- Diphenhydramine - Correct Answer - A. Naloxone
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pg. 4
The tricyclic antidepressants should be prescribed cautiously in patients with:
A. CAD
- Eczema
- Asthma
- Diabetes - Correct Answer - A. CAD
What "onset of action symptoms" should be reviewed with patients who have been newly prescribed an SSRI?
- They will have insomnia for a week.
- They can feel a bit of nausea, but this resolves in about 1 week.
- They will have a huge increase in appetite
- They will not dream. - Correct Answer - B. They can feel a bit of nausea, but this
resolves in about 1 week.
Jaycee has been on Escitalopram for a year and is willing to try tapering off the SSRI.What is the initial dosage adjustment when starting to taper off antidepressants?
- Change dose to every other day dosing for a week
- Reduce dose by 50% for 3-4 days
- Reduce dose by 50% every other day •
- Escitalopram can be stopped abruptly due to its long half-life - Correct Answer - B.
Reduce dose by 50% for 3-4 days
One major drug used to treat bipolar disease is Lithium. Because lithium has a narrow
therapeutic range, it is important to recognize symptoms of toxicity, such as:
- Orthostatic hypotension
- Agitation and irritability
- Drowsiness and nausea
- Painful urination - Correct Answer - C. Drowsiness and nausea
Monitoring of a patient on Gabapentin to treat seizures includes:
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