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NURS 5334 /NURS5334 FINAL EXAM 2025 NEWEST
ACTUAL EXAM COMPLETE EXAM QUESTIONS WITH
DETAILED VERIFIED ANSWERS (100% CORRECT
ANSWERS) /ALREADY GRADED A+ / LATEST
EXAMS!!!
Prescribing basics - Answer-Prescribing is regulated by state BON
Proper RX - Answer-Providers name and address, Telephone DEA Pt name/DOB/Addres Name of Drug, strength, SIG(directions) with indication/Route and frequency, Quantity and signature.
Drug Schedules: Most addictive to least - Answer-1: Heroin,LSD, MJ
2: hydrocodone, cocaine, Methamphetamine, methadone,
oxycodone, meperidine, fentanyl, adderall, ritalin
3: codeine, ketamine, testosterone
4: xanax, valium, soma, ambient, tramadol 1 / 4
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5: antidiarrheal, antitussives, lomotil, lyrica
Pharmicodyamics - Answer-The effects of drug on the body. Receptors are large molecules usually proteins, that interact and mediate the action of drugs
agonist - Answer-produce receptor stimulation and a conformational change every time they bind. Do not need all available receptors to produce a maximum response
Partial agonist - Answer-drugs that have properties in b/w those of full agonist and antagonist. They bind to receptors but when they occupy the receptor sites, they stimulate only some of the receptors.
antagonist - Answer-drugs with affinity for a receptor but with no intrinsic activity. Affinity allows the antagonist to bind to receptors, but lack of intrinsic activity prevents the bound antagonist from causing receptor activation. The block action of drugs (ex. Narcan)
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Bioavailabity - Answer-% of administered dosage of the drug that survives the first pass through the liver and reaches the blood stream
half life - Answer-Time required for the amount of a drug in the body to decline by 50%, drugs with shorter half lives must be administer frequently. 4.5-5.5 times the half life to get steady state and to be limited from the body
what the body does to the drug - Answer-absorption, distribution, metabolism, excretion
Distribution - Answer-movement of absorbed drug in bodily fluids throughout the body to target tissue. Properties
affecting: lipid/water solubility, PH affects ionization of
drug, protein binding, size of molecule (smaller molecules are more able to diffuse)
Tissue: fat, bone, blood/brain barrier (only lipid soluble will
pass), placental barrier (many drugs can pass)
Protein binding - Answer-unbound drug is free which is active, crosses membrane. Low plasma proteins result in 3 / 4
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more free drug. Competition: when 2 highly bound drugs
are given it increases the level of both drugs
Metabolism - Answer-take place in the liver mostly.
Chemical change of a drug structure to:
Enhance excretion, inactivate the drug, increase therapeutic action, active a prodrug (inactive until
metabolized in the body into the active compound, ex:
levodopa), increase or decrease toxicity
CYP450 - Answer-enzymes constitutes the most important of the phase I metabolizing enzymes (account for about 75% of drug metabolism in the liver)
Phase 2: conjugation reaction occur leading to large
increases in hydrophilicity of the substrates rendering them more readily excretable
Substrate - Answer-an agent that is metabolized by an enzyme into a metabolite and product and eventually excreted
Inhibitors - Answer-compete with other drugs for a particular enzyme affecting the metabolism (decreased) of
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