NURS 660 - Psychopharmacology & Advanced Mental Health
Exam 3
Question:
What is central neuropathic pain or central sensitization due to?
Answer:
central disturbance in pain processing (diffuse hyperalgesia/ allodynia
Question:
What does central neuropathic pain or central sensitization respond to?
Answer:
neuroactive compounds that alter levels of neurotransmitters involved in pain transmission, and responsive to nonpharmacologic therapies such as exercise and CBT
- / 4
Question:
What are examples of central neuropathic pain/ central sensitization?
Answer:
Fibromyalgia, IBS, TMJD, Tension headache
Question:
What is the combination of peripheral and central mechanism pain due to?
Answer:
involvement of both inflammatory or mechanical damage to the tissues along with dysfunction in central pain processing
Question:
How to treat a combination of peripheral and central mechanism-related pain
Answer:
need to treat all contributing mechanisms
Question:
Give examples of combination of peripheral/ central mechanism pain
Answer:
low back pain, Rheumatologic diseases that develop into comorbid fibromyalgia 2 / 4
Question:
List the Benzodiazepine Anxiolytics
Answer:
Xanax, Valium, Ativan
Question:
List the labs for Benzodiazepine Anxiolytics
Answer:
Monitor levels of TCA and Dig with concurrent use of Benzos--may increase
those levels. Long term: check liver and CBC periodically.
Question:
Mech of Action of Benzodiazepine Anxiolytics
Answer:
Binds to benzo receptors on postsynaptic GABA-A neuron within CNS including limbic system
Question:
In case of Benzo OD, use what med?
Answer:
Flumazinil
- / 4
Question:
Pregnancy Risk for Benzo's
Answer:
Contraindicated
Question:
What is a non-Benzo Anxiolytic?
Answer:
Buspar
Question:
On what Neurotransmitters does Buspar work?
Answer:
5HT1A and 5HT2 receptors, does not affect GABA receptors, moderate affinity for D2 receptors. 5HT1A partial agonist at pre and post synaptic receptors
Question:
Mechanism of action of Buspar
Answer:
Enhanced serotonergic activity in projections to the amygdala, PFC, Striatum, and thalamus
- / 4