NURS622 Advanced Pharmacology - Exam 1 - Week
- - 1 of 3 - Diabetes
What are the drugs used to treat Type 1 DM? - Correct Answer Insulin Amylin Analog (black box warning for severe hypoglycemia) What are the drugs used to treat Type 2 DM? - Correct Answer Biguanides Meglitinides Sulfonylureas (1st and 2nd generation) Amylin Analog Thiazolidinediones Alpha-Glucosidase Inhibitors Dipeptidyl pedtidase-4 inhibitors (DDP-4) Incretin Analogs or Glucagon-like Peptide Sodium-Glucose Cotransporter 2 Inhibitors Biguanide drug example(s) - Correct Answer metformin Meglitinide drug examples - Correct Answer Nateglimide Repaglinide Sulfonylureas 1st Gen examples - Correct Answer Acetoheamine Chlorpropamide Tolbutamide Tolazamide Sulfonylureas 2nd Gen examples - Correct Answer Glyburide Glipizide Glimepiride Amylin Analog examples and warning - Correct Answer Pramlintide (Symlin) 1 / 2
Do NOT mix with insulin products Thiazolidinediones examples - Correct Answer Rosiglitazone Proglitazone Alpha-glucosidase Inhibitor examples - Correct Answer Acarbose Miglitol DDP-4 Inhibitor examples - Correct Answer Linagliptin Saxagliptin Sitagliptin Incretin Analogs or GLP-1 examples - Correct Answer Exenatide Liraglutide SGLT2 Inhibitor examples - Correct Answer Canaglifozizn Dapaglifozin Type 2 DM Treatment Algorithm - Correct Answer 1st - healthy eating and weight control, patient education, increased physical activity, check AIC in 3 months 2nd - add metformin to 1st and recheck A1C in 3 months 3rd - Add another oral antidiabetic to the metformin and behavior mod, OR add insulin, recheck AIC in 3 months (now 2 meds and BM) 4th - Add another medication - recheck in 3 months (now 3 meds and BM) 5th- combination injectable therapy (basal insulin with addition of mealtime or GLP-1-RA) Metformin* - Correct Answer first line therapy decreases weight gain good for obese patients Indications for insulin therapy - Correct Answer A1C > 10% Random blood glucose >300
- / 2