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HESI Major Depressive Disorder CS Questions and Answers | Latest Version | 2025/2026 | Correct & Verified
What is the therapeutic goal of antidepressant medication?✔✔Improve mood, energy, and functional ability
How long do SSRIs typically take to show clinical improvement?✔✔2 to 4 weeks
What should the nurse teach patients about abruptly stopping antidepressants?✔✔It can cause withdrawal symptoms and relapse
What is the purpose of electroconvulsive therapy (ECT) in depression?✔✔Treat severe or treatment-resistant depression
Which nonverbal sign may indicate depression in a patient?✔✔Poor eye contact and slumped posture
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Which nursing intervention helps a patient with poor appetite due to depression?✔✔Offer small, frequent, nutrient-dense meals
What is the hallmark symptom of major depressive disorder?✔✔Persistent sadness lasting most of the day, nearly every day
Which sleep disturbance is most often seen in major depressive disorder?✔✔Early morning awakening or insomnia
What is the first-line pharmacologic treatment for major depressive disorder?✔✔Selective serotonin reuptake inhibitors (SSRIs)
Which neurotransmitter imbalance is most commonly linked to major depressive disorder?✔✔Serotonin deficiency
What type of therapy helps patients reframe negative thoughts in depression?✔✔Cognitive behavioral therapy (CBT)
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Which physical symptom often accompanies major depressive disorder?✔✔Loss of appetite and unintended weight change
Which vital sign change can occur in severe depression?✔✔Low energy with psychomotor retardation
What is an essential nursing priority in major depressive disorder?✔✔Assessing for suicidal thoughts or behaviors
Which lab test may be ordered to rule out medical causes of depression?✔✔Thyroid function tests
What is anhedonia in major depressive disorder?✔✔Loss of interest or pleasure in activities once enjoyed
Which population is at greater risk for suicide in depression?✔✔Older adult men
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