1
Biology Cell Cycle and Cancer Questions and Answers Latest Version Graded A+
The cell cycle is regulated by various checkpoints. What is the purpose of the G1 checkpoint?✔✔ To ensure the cell has adequate size and necessary nutrients to proceed to DNA replication
What phase of the cell cycle is characterized by the replication of DNA?✔✔ S phase
During which phase of the cell cycle does the cell prepare for division by synthesizing proteins and organelles?✔✔ G2 phase
What is the primary function of cyclins in the regulation of the cell cycle?✔✔ To activate cyclin-dependent kinases (CDKs) that regulate the progression of the cell cycle
How does the p53 protein act as a tumor suppressor during the cell cycle? 1 / 2
2
✔✔ It detects DNA damage and can trigger cell cycle arrest or apoptosis if the damage is irreparable
What is the role of the M checkpoint in the cell cycle?✔✔ To ensure that the chromosomes are properly aligned on the mitotic spindle before the cell proceeds to anaphase
What happens if the cell cycle progresses without proper checks at the G1 checkpoint?✔✔ The cell may proceed to DNA replication with damaged or insufficient DNA, increasing the risk of mutations
Which phase of the cell cycle involves the division of the nucleus?✔✔ M phase (mitosis)
What is the result if there is a failure of the spindle assembly checkpoint during mitosis?✔✔ The chromosomes may not segregate properly, leading to aneuploidy or other genetic abnormalities
How does uncontrolled cell division relate to cancer?
- / 2