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Psychopharmacology (Antidepressants) Questions and Answers | Latest Version | 2025/2026 | Correct & Verified
What is a common side effect during the first weeks of taking SSRIs like fluoxetine?✔✔ Nausea and headache
Why should a client avoid abruptly stopping antidepressants?✔✔ It may cause withdrawal symptoms or relapse of depression
What is the therapeutic effect of selective serotonin reuptake inhibitors (SSRIs)?✔✔ Increase serotonin levels in the brain to improve mood
What dietary restriction is essential when taking monoamine oxidase inhibitors (MAOIs)?✔✔ Avoid foods high in tyramine
What is a dangerous side effect of combining SSRIs with MAOIs or other serotonergic drugs?✔✔ Serotonin syndrome
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What symptom is commonly associated with serotonin syndrome?✔✔ Muscle rigidity, agitation, and high fever
What time of day is best to take most SSRIs?✔✔ In the morning to reduce risk of insomnia
What is an expected effect of tricyclic antidepressants like amitriptyline?✔✔ Sedation and dry mouth
Why should bupropion be avoided in clients with a history of seizures?✔✔ It lowers the seizure threshold
What is the purpose of prescribing antidepressants like duloxetine in chronic pain?✔✔ They help reduce both depression and neuropathic pain
What lab value should be monitored in clients taking tricyclic antidepressants?✔✔ ECG to monitor for cardiac effects
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What is an early sign that a client may be responding to antidepressant treatment?✔✔ Improved sleep and appetite
What should a nurse monitor for in a client beginning antidepressant therapy for depression?✔✔ Worsening suicidal thoughts, especially in the first weeks
What teaching should be given to a client taking paroxetine?✔✔ May cause sexual dysfunction and weight gain
What is the action of SNRIs like venlafaxine?✔✔ Increase both serotonin and norepinephrine in the brain
What is a common reason clients discontinue antidepressants prematurely?✔✔ Delayed onset of symptom relief
What should be avoided when taking MAOIs to prevent a hypertensive crisis?✔✔ Aged cheeses, cured meats, and fermented products
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