QUESTIONS WITH CORRECT ANSWERS

NR 293 Pharm Exam 1 Chamberlain

QUESTIONS WITH CORRECT ANSWERS

REVIEWED 2025/2026

Risks for injury - ANSWER know that anything can be a possible risk for patient injury

• rights of medicine administration - ANSWER right

patient, right dose, right medication, right time, right documentation, right route, right reason, right response what is a prototype - ANSWER the first drug of a class that all others are based from (ex- morphine) what is pharmacokinetics - ANSWER what the body does to the drug what is pharmacodynamics - ANSWER what the drug does to the body bioavailability - ANSWER what portion of the drug that entered the circulation can have an effect on the body 1 / 4

first pass effect - ANSWER a drug enters the GI tract and is filtered to the liver where some is destroyed what enzymes work in the liver - ANSWER P-450 enzymes if a patient has cirrhosis of the liver, what will happen when they take a medication? - ANSWER When the medication passes through the liver for the first pass, there will be less P-450 enzymes so the bioavailability of the medication will be higher and it will circulate in the bloodstream longer.half life - ANSWER time required for 50% of the drug to be removed from the body Pharmacotherapeutics - ANSWER treatment of conditions enteral route - ANSWER through the GI tract parenteral tract - ANSWER outside the GI tract how is medication absorption different for neonates and children? - ANSWER they have less gastric acid to break down medications and availability is higher 2 / 4

why do more drugs enter neonate and children's brains, why are meds not as easily excreted/destroyed by liver and kidneys ? - ANSWER immature BBB, liver, and kidneys Polypharmacy - ANSWER The use of multiple medications on a regular basis during which phase of the nursing process does a nurse prioritize the nursing diagnoses? - ANSWER planning the nurse recognizes that drugs given by which route will be altered by the first pass effect?

• oral
• sublingual
• subcutaneous
• IV
• rectal - ANSWER oral and rectal

the nurse is reviewing a list of a patient's medications and notes one of the drugs has a low therapeutic index. what does this mean? - ANSWER the difference between a therapeutic dose and a toxic dose are very close together when drug A is an enzyme inhibitor of drug B, the nurse will anticipate what result of drug B? - ANSWER level of drug B could rise to toxicity 3 / 4

A drug is highly protein bound, what does this mean? - ANSWER it will have a longer duration of action do no harm is what ethical principle? - ANSWER nonmaleficence Which legal act required drug manufacturers to establish the safety and efficacy of a new drug before its approval for use? - ANSWER Kefauver-Harris, amendment of 1962 over the counter drugs (otc) are - ANSWER nonprescription drugs that are used for short term treatment what herbal supplement is used to promote sleep and relaxation, prolonged use can cause yellow discoloration of nails, risk for liver toxicity - ANSWER kava herbal supplement used to decrease nausea and vomiting induced by chemotherapy

• ANSWER ginkgo

which drug classes are used as OTC remedies ?

• NSAIDs
• cold remedies
• antibiotics

d.smoking deterrent drugs

• antihypertensive drugs
• histamine 2 (H2) blockers - ANSWER A, B,D,F
• / 4