NUR 2474 Pharmacology for Professional Nursing
Quiz 1 Pharmacology
Question:
Action of Sinemet (levodopa/carbidopa)
Answer:
Crosses BBB and is transported to the nerve cells in brain to produce dopamine. Dopamine is then converted for the nerve cells to use a neurotransmitter.
Question:
Sinemet (levodopa/carbidopa) adverse drug reactions
Answer:
- darkening urine or sweat
- nausea/vomiting
- dyskinesia, tremors, and twitching
- on and off Parkinson's episodes
- orthostatic postural hypotension
- symptoms of psychosis, paranoia, or hallucinations (rare)
- / 3
Question:
Avoid what type of food with Sinemet (carbidopa/levodopa)?
Answer:
High protein foods (non or low protein foods with medication)
Question:
CHOLINESTERASE INHIBITOR: Aricept (donepezil) action
Answer:
Prevention of the enzyme acetylcholinesterase from inactivating acetylcholine to increase amount of acetylcholine available at receptor sites in brain for Alzheimer's
Question:
Aricept (donepezil) adverse effects
Answer:
- CNS effects
- insomnia
- dizziness
- headache
- N/V (monitor for coffee ground emesis or stool + give with food)
- bradycardia
- / 3
Question:
What can you not give with Aricept (donepezil)?
Answer:
NSAIDS, children, + people with Hx of GI bleed
Question:
When do you give Aricept (donepezil)?
Answer:
Bedtime with or without food
Question:
NDMA RECEPTOR ANTAGONIST: Namenda (memantine) action
Answer:
Block glutamate from stimulating NMA receptors resulting in decreased calcium influx into neurons in the brain
Question:
What does Namenda (memantine) do?
Answer:
Can slow decline of cognitive and physical functioning
- / 3