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Rasmussen College MDC 2 Exam 1 Study Guide
- What are the stages of cell growth in cancer development
ANS 1. Initiation
- Promotion
- Progression
- Metastasis
- What happens during Initiation phase during cancer cell growth
ANS normal cells become damaged and leads to development of cancer (Malignant Transforma- tion) this is irreversible
- What happens during the promotion stage during cancer cell growth
ANS -re- peat exposure to carcinogen enhances cell growth which leads to mutation 1 / 2
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-enhanced cell growth of cells by promotors (like hormones primarily estrogen) -period between initiation and growth into a tumor is called a latency period
- What happens during the progression stage of cancer cell growth
ANS -An increase in the production of malignant cells -after a tumor reach 1 cm, it already has 1 billion cells -when it builds its own blood supply it becomes a health problem
- What happens during the Metastasis stage of cancer cell growth
ANS -move- ment of cells from the primary site and establishing remote colonies
- Malignant vs. Benign
: Malignant
-Anaplasia-loss of appearance of parent cell -A larger nuclear-to-cytoplasmic ration -Specific functions are lost-serve NO purpose -Loose adherence-loosely bound due to the lack fo fibronectin production -migration-spreads easily (metastasis) -Contact inhibition does not occurs -Rapid or continuous cell division
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