Clinical Immunology and Serology 4th Edition Stevens Test Bank Chapter 1. Introduction to Immunity and the Immune System
Multiple Choice
1. Eosinophils are involved in the immune response against:
- viruses.
- intracellular bacteria.
- parasites that cannot be phagocytized.
- extracellular bacteria.
ANS: C
- Which of the following are components of both innate and adaptive immune responses?
- Immunoglobulins
- T helper cells
- Macrophages
- B cells
ANS: C
- The process by which leukocytes are attracted to a specific area by chemical messengers is called:
- diapedesis.
- degranulation.
- chemotaxis.
- opsonization.
ANS: C
- Which of the following is a characteristic of natural killer cells?
- They mature in the thymus.
- They are smaller than B and T cells.
- They are a type of lymphocyte.
- They are part of the adaptive immune system.
ANS: C
- Which of the following best describes diapedesis?
- Movement toward increasing concentrations of a cytokine
- Attachment of immunoglobulin to target cells 1 / 4
- Movement through blood vessel walls as cells exit the circulation
- Engulfment of target cells
ANS: C
6. The most effective phagocytic and antigen-presenting cell is the:
- neutrophil.
- monocyte.
- dendritic cell.
- macrophage.
ANS: C
- Which of the following is characteristic of natural immunity?
- It involves memory.
- T lymphocytes play a major role.
- It involves specificity.
- Mechanisms are always present and fully functional.
ANS: D
8. All of the following cells are considered part of natural immunity EXCEPT:
- eosinophils.
- B lymphocytes.
- monocytes.
- neutrophils.
ANS: B
- Where does the specific immune response to a foreign antigen mainly occur?
- Lymph nodes
- Blood
- Bone marrow
- Skin
ANS: A
- Which white cell in the peripheral blood migrates into tissue to become a macrophage?
- Eosinophil
- Basophil
- Neutrophil 2 / 4
- Monocyte
ANS: D
- A white blood cell that is 16 to 18 micrometers in diameter, has a horseshoe-shaped nucleus, and is
capable of phagocytosis is a:
- neutrophil.
- eosinophil.
- basophil.
- monocyte.
ANS: D
- Pasteur's discovery that older bacterial cultures would not cause disease in chickens but would protect
them from subsequent infection with more virulent strains is an example of:
- attenuated vaccine.
- natural immunity.
- passive immunity.
- cross-immunity.
ANS: A
13. Antibodies are secreted by:
- plasma cells.
- B cells.
- T cells.
- dendritic cells.
ANS: A
- Which of the following is characteristic of mucosal-associated lymphoid tissue?
- It is one of the primary lymphoid organs.
- It clears pathogens from the bloodstream.
- It includes the tonsils and the appendix.
- It includes the liver and spleen.
ANS: C
15. Acquired (adaptive) immunity can be characterized as:
- nonspecifically activated.
- immediately responsive. 3 / 4
- neutrophil dependent.
- involving memory.
ANS: D
- Which of the following is NOT a characteristic of neutrophils?
- Congregate in the marginating pool in blood vessels
- Capable of diapedesis
- Granules that become bright orange with Wright stain
- Segmented nucleus
ANS: C
17. The function of NK cells is to:
- produce antibody.
- phagocytize bacteria.
- present antigen to T cells.
- kill target cells such as tumor and virally infected cells.
ANS: D
18. All of the following are involved in adaptive immunity EXCEPT:
- memory.
- lymphocytes.
- specificity.
- neutrophils.
ANS: D
- Which of the following is NOT a characteristic of a lymph node?
- Filters interstitial fluid draining from tissues
- Colonized with T and B cells
- Between 1 and 25 mm in size
- Considered a primary or central lymphoid organ
ANS: D
20. All of the following are considered part of natural immunity EXCEPT:
- eosinophils.
- lymphocytes.
- acute-phase reactants.
- / 4