TEST BANK FOR BASIC AND CLINICAL PHARMACOLOGY

TEST BANK FOR BASIC AND CLINICAL PHARMACOLOGY

16TH EDITION KATZUNG’S TESTBANK /ALL CHS 1-

66/COMPLETE GUIDE 2024-2025

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CH 1. Introduction: The Nature of Drugs & Drug Development & Regulation

• A nurse working in radiology administers iodine to a client who is having a

computed tomography (CT) scan. The registered nurse working on the oncology unit administers chemotherapy to clients who have cancer. At the Public Health Department, a registered nurse administers a measles-mumps- rubella (MMR) vaccine to a 14-month-old child as a routine immunization.Which branch of pharmacology best describes the actions of all three registered nurses?

• Pharmacoeconomics
• Pharmacotherapeutics
• Pharmacodynamics
• Pharmacokinetics

RIGHT ANSWER:- B

Explanation:->>>

Pharmacology is the study of the biologic effects of chemicals. Registered nurses are involved with clinical pharmacology or pharmacotherapeutics, which is a branch of pharmacology that deals with the uses of drugs to treat, prevent, and diagnose disease. The radiology registered nurse is administering a drug to help diagnose a disease. The oncology registered nurse is administering a drug to help treat a disease. Pharmacoeconomics includes any costs involved in drug therapy.Pharmacodynamics involves how a drug affects the body and pharmacokinetics is how the body acts on the body.

• When involved in phase III drug evaluation studies, what

responsibilities would the registered nurse have?

• Working with animals who are given experimental drugs
• Choosing appropriate clients to be involved in the drug study
• Monitoring and observing clients closely for adverse effects
• Conducting research to determine effectiveness of the drug
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RIGHT ANSWER:- C

Explanation:->>>

Phase III studies involve use of a drug in a vast clinical population in which clients are asked to record any symptoms they experience while taking the drugs. Registered nurses may be responsible for helping collect and analyze the information to be shared with the Food and Drug Administration (FDA) but would not conduct research independently because registered nurses do not prescribe medications. Use of animals in drug testing is done in the preclinical trials. Select clients who are involved in phase II studies to participate in studies where the participants have the disease the drug is intended to treat. These clients are monitored closely for drug action and adverse effects. Phase I studies involve healthy human volunteers who are usually paid for their participation. Registered nurses may observe for adverse effects and toxicity.

• A physician has ordered intramuscular (IM) injections of morphine, a

narcotic, every 4 hours as needed for pain in a motor vehicle accident victim.The registered nurse is aware this drug has a high abuse potential. Under what category would morphine be classified?

• Schedule I
• Schedule II
• Schedule III
• Schedule IV

RIGHT ANSWER:- B

Explanation:->>>

Narcotics with a high abuse potential are classified as Schedule II drugs because of severe dependence liability. Schedule I drugs have high abuse potential and no accepted medical use. Schedule III drugs have a lesser abuse potential than II and an accepted medical use. Schedule IV drugs have low abuse potential and limited dependence liability.

• What concept is considered when generic drugs are substituted for brand

name drugs?

• Bioavailability

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