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UTMB ADVANCED PATHOPHYSIOLOGY 5355
Exam 3 Modules 5 & 6 Questions With Complete Solutions
Question 1: Biogenic Amine Theory linked to depression
CORRECT ANSWER : Deficiency of neurotransmitters in brain
of norepinephrine, dopamine, and/or serotonin. Particularly, a decrease in receptor binding with serotonin.
Question 2: Neurotransmitter Receptor Hypothesis linked to
depression
CORRECT ANSWER : A deficiency of monoamine
neurotransmitters at neuronal synapses.
Question 3: Antidepressants increase
CORRECT ANSWER : Neuronal synaptic levels of monoamine
neurotransmitters.
Question 4: If you have more receptors than neurotransmitters
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CORRECT ANSWER : Neurotransmitters do not have time to
re-charge thus, they do not function properly.
Question 5: Hypothalamic-Pituitary-Adrenal (HPA) System
Dysregulation
CORRECT ANSWER : HPA system dysregulation with
excessive glucocorticoid secretion is found in a large percentage of people suffering from major depression.
Question 6: Patho of Alzheimer's includes - plaque formation,
presence of --, with decreased levels of -
CORRECT ANSWER : Amyloid B, neurofibrillary tangles,
acetylcholine these disrupt impulse transmission
Question 7: Neurofibrillary tangles
CORRECT ANSWER : are a deformation of the structure that
carries nutrients to neurons of the brain.
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Question 8: Decreased levels of choline acetyl transferase and
acetylcholine is associated with
CORRECT ANSWER : Memory loss
Question 9: Most common cause of dementia
CORRECT ANSWER : Alzheimer's disease fatal 5-10 years
Question 10: Characteristics of Alzheimer's
CORRECT ANSWER : Loss of memory, language , inability to
learn new things, dysfunction, delusions, cannot perform ADLs, majorly effects social life
Question 11: Parkinson's Disease is
CORRECT ANSWER : Chronic motor progressive neuro-
degenerative known as a shaking palsy
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Question 12: Parkinson's disease is associated with
CORRECT ANSWER : basal ganglia dysfunction and atrophy of
neurons in the substantia nigra that produce dopamine;
Question 13: Characteristics of Parkinson's disease
CORRECT ANSWER : Tremors at rest, rigidity, bradykinesia,
muscular rigidity and postural abnormalities.
Question 14: 2 Main Categories of CVA
CORRECT ANSWER : Hemorrhagic and Ischemic
Question 15: Hemorrhagic CVA
CORRECT ANSWER : Blood produces inflammatory reaction,
swelling, displaces brain tissue and increases ICP