Walden NURS 6501 Advanced

6 Walden NURS 6501 Advanced Pathophysiology Week 1 1.refers to the terminal location of centromere on chromosomes 13, 14, 15, 21, and 22 ANS acrocentric 2.the situation in which multiple alleles at a single locus can produce one or more disease phenotypes.ANS allelic heterogeneity 3.refers ro mutations that cause a complete loss of function for the respective gene, and therefore yield the same phenotype as a complete gene deletion. 1 / 2

6 ANS - amorphic 4.a general term used to denote any unbalanced chromosome complement- ANS aneuploidy 5.refers to mutations that when present in heterozygous form opposite a nonmutant allele will result in a phenotype similar to homozygous for loss of function alleles.ANS antimorphic 6.the situation in which individuals or families in a genetic study are not representative of the general population because of the way in which they are identified ANS ascertainment bias 7.located on chromosomes 1-22 rather than x or y