NR-565 Advanced Pharmacology Fundamentals
Week 6 Quiz
MOA of leukotrienes?
Correct Answer:
reduces smooth muscle constriction, reduces inflammation
- leukotrienes available
Correct Answer:
montelukast, zafirlukast, zileuton
what line of therapy are leukotrienes?
Correct Answer:
2nd line of therapy
serious potential adverse effects of leukotrienes
Correct Answer:
neuropsychiatric effects (depression, suicidal ideation)
- / 2
monitoring required with zileuton?
Correct Answer:
LFTs to be checked once a month for 3 months, then every 2-3 months a year
most common adverse effects of zafirlukast
Correct Answer:
GI disturbances, arthralgia/myalgia
what medication should be avoided with LTRA d/t risk for toxic blood levels
Correct Answer:
theophylline
- approved indications of Montelukast
Correct Answer:
maintenance therapy for asthma, allergic rhinitis, exercise induced bronchospasm (EIB)
MOA of cromolyn
Correct Answer:
prophylactic use for allergic rhinitis, reduces/suppresses inflammation
- / 2