WGUl D115l Pre-l Assessmentl (Latestl 2025/l 2026l Update)l Advancedl Pathophysiologyl forl thel Advancedl Practicel Nursel Review|l Questionsl &l Answers|l Gradel A|l 100%l Correctl (Verifiedl Solutions)
Q:l Al childl presentsl tol al clinicl withl al whitel pupillaryl reflexl notedl inl thel rightl eye.l Thel childl isl constantlyl cryingl and rubbingl herl eyes.l Anl advancedl practicel registeredl nursel (APRN)l performsl al completel ophthalmologicl examination andl ordersl severall diagnosticl tests.l Basedl onl thel findings,l al diagnosisl ofl retinoblastomal isl confirmed.Whatl isl thel pathologicall mechanisml ofl thisl disorder?l Autosomall dominantl linkedl tol genesl resultsl inl mutationsl onl chromosomel 21 l Deficiencyl ofl hexosaminidasel causesl accumulationl enzymesl thatl damagel thel brain l Mutationsl ofl al genel onl chromosomel 13q14l leadl tol neoplasticl proliferationl ofl cells l Invasionl ofl astrocytomasl ofl thel brainl structurel destroysl normall defenses
Answer:
Mutationsl ofl al genel onl chromosomel 13q14l leadl tol neoplasticl proliferationl ofl cells
Q:l Al patientl isl seenl byl anl advancedl practicel registeredl nursel (APRN)l atl al primaryl carel clinicl forl follow-upl tol discuss abnormall resultsl ofl testingl forl peripherall nervousl systeml impairment.Whichl diagnosisl shouldl thel APRNl suspect?l Autonomicl hyperreflexia l Diffusel axonall injury l Spinall cordl injury l Demyelinatingl polyneuropathy
Answer:
Demyelinatingl polyneuropathy
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Q:l Al patientl isl seenl inl thel clinicl afterl beingl al restrainedl passengerl inl al carl accidentl thel previousl week.l Thel patientl continuesl tol havel intermittentl headachesl andl hasl noticedl periodsl ofl forgetfulness.l Assessmentl findingsl includel a BPl ofl 130/82l mml Hgl andl anl apicall pulsel ratel ofl 72l bpm.l Anl advancedl practicel registeredl nursel (APRN)l isl concerned thatl thel symptomsl mightl steml froml al specificl process.Whichl processl shouldl thel APRNl bel concernedl about?l Decreasedl cerebrall perfusion l Subarachnoidl hemorrhage l Cerebrall concussion l Skulll fracture
Answer:
Cerebrall concussion
Q:l Anl advancedl practicel registeredl nursel (APRN)l isl examiningl anl adolescentl patientl whol describesl hearingl voices tellingl herl tol gatherl weaponsl becausel thel governmentl isl tryingl tol controll her.l Thel patientl alsol describesl feelingsl of happinessl relatedl tol al tragicl personall event.Whatl isl thel probablel diagnosis?l Bipolarl disorder l Obsessivel compulsivel disorder l Panicl attack l Schizophrenia
Answer:
Schizophrenia
Q:l Al patientl isl seeingl anl advancedl practicel registeredl nursel (APRN)l inl anl occupationall healthl setting.l Thel patientl has beenl referredl byl employeel assistancel forl recklessl andl self-destructivel behaviorsl andl al violentl incidentl atl work regardingl al fellowl employee.l Thel APRNl suspectsl post-traumaticl stressl disorderl (PTSD).Whichl diagnosticl clusterl ofl PTSDl isl thel patientl exhibiting?l Negativel cognitions l Avoidance l Reexperiencing l Arousal
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Answer:
Arousal
Q:l Al 45-year-oldl malel patientl withl alteredl testosteronel levelsl needsl treatment.l Anl advancedl practicel registeredl nurse (APRN)l isl awarel thatl threel factorsl affectl hormonel targetl celll responsesl whenl determiningl al treatmentl approach.Whichl factorl shouldl bel consideredl byl thel APRN?l Limitedl concentrationl ofl organs l Changel ofl targetl celll sensitivity l Affinityl ofl receptorl forl thel hormones l Limitedl numberl ofl targetl celll receptors
Answer:
Affinityl ofl receptorl forl thel hormones
Q:l Al patientl isl beingl admittedl tol anl ICUl afterl al traumaticl brainl injury.l Duringl thel firstl fewl hours,l thel patientl develops polydipsia,l andl hisl urinaryl catheterl isl drainingl largel volumesl ofl dilutel urine.l Anl advancedl practicel registeredl nurse (APRN)l runsl somel tests,l andl thel seruml labl valuesl showl hypernatremial andl hyperosmolarity.Whichl diagnosisl shouldl thel APRNl identifyl forl thisl patient?l Diabetesl insipidus l Hypopituitarism l Hyperpituitarism l Syndromel ofl inappropriatel antidiureticl hormone
Answer:
Diabetesl insipidus
Q:l Anl advancedl practicel registeredl nursel (APRN)l examinesl al patientl andl notesl thel
followingl findings:
adiposel tissuel inl thel trunk,l facial,l andl cervicall areas striael ofl skin easyl bruising thinl extremities hypertension cardiacl hypertrophy 3 / 4
increasedl faciall hair hypercortisolism Whichl pathologicall mechanisml ofl thel diseasel processl isl associatedl withl thesel symptoms?l Excessivel autonomousl secretionl ofl aldosteronel duel tol lackl ofl itsl principall regulator,l angiotensinl II l Insufficientl ADHl activity,l excretionl ofl largel volumesl ofl dilutel urine,l andl increasedl plasmal osmolality l Hypomagnesemial inhibitsl PTHl secretion,l impairmentl ofl resorptionl ofl calciuml froml bone,l and regulationl ofl calciuml reabsorptionl froml thel renall tubules l Secretionl ofl bothl cortisoll andl adrenall androgensl isl increasedl andl inhibitionl ofl corticotropin-releasing hormonel (CRH)l secretion
Answer:
Secretionl ofl bothl cortisoll andl adrenall androgensl isl increasedl andl inhibitionl ofl corticotropin-releasing hormonel (CRH)l secretion
Q:l Al patientl presentsl tol thel emergencyl departmentl complainingl ofl difficultyl swallowing,l drooling,l andl painl radiatingl to thel leftl ear.l Duringl thel assessment,l anl advancedl practicel registeredl nursel (APRN)l notesl unilaterall redness,l left swollenl tonsil,l andl al displacedl uvula.Whichl diagnosisl shouldl thel APRNl makel forl thisl patient?l Bartholin'sl abscess l Pharyngitis l Retropharyngeall abscess l Periodontitis
Answer:
Retropharyngeall abscess
Q:l Anl advancedl practicel registeredl nursel (APRN)l isl performingl anl assessmentl onl al newbornl inl al nursery.l Thel infant's headl isl atraumaticl withl anl open,l flat,l andl softl anteriorl fontanel.l Thel pupilsl arel equal,l round,l andl reactivel tol light withl normall lightl reflex.l Uponl occlusionl ofl thel leftl nare,l thel infantl startles,l becomesl irritable,l andl isl unablel to
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